Article
Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition.
Cell reports - 29 Aug 2017
Wyeth Megan S, Pelkey Kenneth A, Yuan Xiaoqing, Vargish Geoffrey, Johnston April D, Hunt Steven, Fang Calvin, Abebe Daniel, Mahadevan Vivek, Fisahn André, Salter Michael W, McInnes Roderick R, Chittajallu Ramesh, McBain Chris J
Abstract excerpt
Although Netos are considered auxiliary subunits critical for kainate receptor (KAR) function, direct evidence for their regulation of native KARs is limited. Because Neto KAR regulation is GluK subunit/Neto isoform specific, such regulation must be determined in cell-type-specific contexts. We demonstrate Neto1/2 expression in somatostatin (SOM)-, cholecystokinin/cannabinoid receptor 1 (CCK/CB1)-, and...
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