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Article

Combined IDH1 mutation and MGMT methylation status on long-term survival of patients with cerebral low-grade glioma.

Clinical neurology and neurosurgery - 1 Nov 2015

Tanaka Kazuhiro, Sasayama Takashi, Mizukawa Katsu, Takata Kumi, Sulaiman Nor Shazrina, Nishihara Masamitsu, Kohta Masaaki, Sasaki Ryohei, Hirose Takanori, Itoh Tomoo, Kohmura Eiji

Abstract excerpt

OBJECTIVE: The management of low-grade glioma (LGG) still remains controversial because the effectiveness of early and extensive resection is unclear, and the use of radiation therapy or chemotherapy is not well-defined. In particular, the importance of prognostic factors for survival remains a matter of discussion. The purpose of this study was to validate prognostic factors for survival in patients with LGG....

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Source

Identifiers

PMID: 26276726
DOI: 10.1016/j.clineuro.2015.07.019

Genes

IDH1
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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