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Article

Chloroquine inhibits the malignant phenotype of glioblastoma partially by suppressing TGF-beta.

Investigational new drugs - 1 Oct 2015

Roy Laurent-Olivier, Poirier Marie-Belle, Fortin David

Abstract excerpt

BACKGROUND: Glioblastoma (GBM), the most common and aggressive primary brain tumor, is characterized by excessive brain infiltration which prevents the complete surgical resection. These tumors also display treatment non-compliance and responses to standard therapy are invariably transient; consequently, the prognosis barely exceeds 14 months and recurrence is inevitable. Accordingly, several new treatment...

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Source

Identifiers

PMID: 26271735
DOI: 10.1007/s10637-015-0275-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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