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Chlorpromazine Induces Cytotoxic Autophagy in Glioblastoma Cells via Endoplasmic Reticulum Stress and Unfolded Protein Response

2021-09-22

Abstract excerpt

<title>Abstract</title> <p>BackgroundGlioblastoma (GBM; grade IV glioma) is characterized by a very short overall survival time and extremely low 5-year survival rates. We intend to promote experimental and clinical research on rationale and scientifically driven drug repurposing. This may represent a safe and often inexpensive way to propose novel pharmacological approaches to GBM . Our precedent work describes...

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Literature Corpus work
7517cff8-821b-5fff-a7a1-dad8faa62c16
DOI
10.21203/rs.3.rs-910497/v1
Open publication

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Chlorpromazine Induces Cytotoxic Autophagy in Glioblastoma Cells via Endoplasmic Reticulum Stress and Unfolded Protein ResponseDOI 10.21203/rs.3.rs-910497/v1
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