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Article

A combination of IFN-β and temozolomide in human glioma xenograft models: implication of p53-mediated MGMT downregulation

12 Jun 2007

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Share to Cancer-related Molecular Pathways
Share to Epigenetics and DNA Methylation
Share to Glioma Diagnosis and Treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 17564708
DOI: 10.1007/s00280-007-0520-x

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A combination of IFN-β and temozolomide in human glioma xenograft models: implication of p53-mediated MGMT downregulationPMID 17564708Read ↗

Effect of IFN-β on human glioma cell lines with temozolomide resistanceSemantic proximity Read ↗

MGMT in TMZ-based glioma therapy: Multifaceted insights and clinical trial perspectivesSemantic proximity Read ↗

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Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft modelSemantic proximity Read ↗

IKBKE enhances TMZ-chemoresistance through upregulation of MGMT expression in glioblastomaSemantic proximity Read ↗

Alkylpurine–DNA–N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patientsSemantic proximity Read ↗

Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O(6)-methylguanine DNA-methyltransferase.Semantic proximity Read ↗

Knockdown of hTERT and concurrent treatment with interferon-gamma inhibited proliferation and invasion of human glioblastoma cell linesSemantic proximity Read ↗

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenograftsSemantic proximity Read ↗

O<sup>6</sup>‐methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cellsSemantic proximity Read ↗

Immunohistochemical assessment of MGMT expression and p53 mutation in glioblastoma multiforme.Semantic proximity Read ↗

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