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Article

In-Vivo Gene Signatures of Mycobacterium tuberculosis in C3HeB/FeJ Mice.

PloS one - 1 Jan 2015

Gautam Uma Shankar, Mehra Smriti, Kaushal Deepak

Abstract excerpt

Despite considerable progress in understanding the pathogenesis of Mycobacterium tuberculosis (Mtb), development of new therapeutics and vaccines against it has proven difficult. This is at least in part due to the use of less than optimal models of in-vivo Mtb infection, which has precluded a study of the physiology of the pathogen in niches where it actually persists. C3HeB/FeJ (Kramnik) mice develop human-like...

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Identifiers

PMID: 26270051
DOI: 10.1371/journal.pone.0135208
PMCID: PMC4535907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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