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Article

mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis.

Journal of bacteriology - 1 Oct 2009

Abomoelak Bassam, Hoye Elizabeth A, Chi Jing, Marcus Sarah A, Laval Francoise, Bannantine John P, Ward Sarah K, Daffé Mamadou, Liu Hong Di, Talaat Adel M

Abstract excerpt

Latent tuberculosis represents a high-risk burden for one-third of the world population. Previous analysis of murine tuberculosis identified a novel transcriptional regulator encoded by Rv0348 that could control the establishment of persistent tuberculosis. Disruption of the Rv0348 gene from the genome of the virulent H37Rv strain of Mycobacterium tuberculosis revealed a global impact on the transcriptional...

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Share to Electrophoretic Mobility Shift Assay
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Inbred BALB C

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Source

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Identifiers

PMID: 19648248
DOI: 10.1128/JB.00778-09
PMCID: PMC2747884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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