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Article

DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture.

Journal of virology - 1 Oct 2015

Grünvogel Oliver, Esser-Nobis Katharina, Reustle Anna, Schult Philipp, Müller Birthe, Metz Philippe, Trippler Martin, Windisch Marc P, Frese Michael, Binder Marco, Fackler Oliver, Bartenschlager Ralf, Ruggieri Alessia, Lohmann Volker

Abstract excerpt

UNLABELLED: All major types of interferon (IFN) efficiently inhibit hepatitis C virus (HCV) replication in vitro and in vivo. Remarkably, HCV replication is not sensitive to IFN-γ in the hepatoma cell line Huh6, despite an intact signaling pathway. We performed transcriptome analyses between Huh6 and Huh-7 cells to identify effector genes of the IFN-γ response and thereby identified the DExD/H box helicase DEAD...

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Share to DEAD Box Protein 58
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26269178
DOI: 10.1128/JVI.01297-15
PMCID: PMC4580188

Genes

DDX60

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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