Article
Impairment of dendritic cell function and induction of CD4(+)CD25(+)Foxp3(+) T cells by excretory-secretory products: a potential mechanism of immune evasion adopted by Echinococcus granulosus.
BMC immunology - 13 Aug 2015
Wang Ying, Zhou Hejun, Shen Yujuan, Wang Yanjuan, Wu Weiping, Liu Haipeng, Yuan Zhongying, Xu Yuxin, Hu Yuan, Cao Jianping
Abstract excerpt
BACKGROUND: Cystic echinococcosis, caused by infection with Echinococcus granulosus, is one of the most widespread zoonotic helminth diseases. Modulation of host responses is an important strategy used by helminth parasites to promote infection. To better understand the mechanisms adopted by E. granulosus to escape host immune responses, we investigated the effects of excretory-secretory products (ES) and adult...
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