Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway.

Parasites & vectors - 14 Nov 2019

Wang Hui, Zhang Chuan-Shan, Fang Bin-Bin, Li Zhi-De, Li Liang, Bi Xiao-Juan, Li Wen-Ding, Zhang Ning, Lin Ren-Yong, Wen Hao

Abstract excerpt

BACKGROUND: Larvae of Echinococcus granulosus (sensu lato) dwell in host organs for a long time but elicit only a mild inflammatory response, which indicates that the resolution of host inflammation is necessary for parasite survival. The recruitment of alternatively activated macrophages (AAMs) has been observed in a variety of helminth infections, and emerging evidence indicates that AAMs are critical for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Echinococcosis
Share to Echinococcus granulosus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophage Activation

Share to Macrophages, Peritoneal

Share to Oncogene Protein v-akt

Share to Peroxiredoxins

Share to Specific Pathogen-Free Organisms

Share to TOR Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 31727141
DOI: 10.1186/s13071-019-3786-z
PMCID: PMC6857240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway.PMID 31727141Read ↗

Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages.Semantic proximity Read ↗

The effects of <i>E. granulosus</i> PSCs proteins on host immune cells were elucidated through Transcriptomic and Metabolomic analysesSemantic proximity Read ↗

Hepatic macrophages play critical roles in the establishment and growth of hydatid cysts in the liver during Echinococcus granulosus sensu stricto infection.Semantic proximity Read ↗

AntigenB drives M1/M2 polarization following Echinococcus granulosus infection in inflammatory bowel diseaseSemantic proximity Read ↗

Echinococcus multilocularis serpin regulates macrophage polarization and reduces gut dysbiosis in colitisSemantic proximity Read ↗

Impairment of dendritic cell function and induction of CD4(+)CD25(+)Foxp3(+) T cells by excretory-secretory products: a potential mechanism of immune evasion adopted by Echinococcus granulosus.Semantic proximity Read ↗

Role of TIM-1+ Regulatory B Cells in Hepatic Alveolar Echinococcosis: Implications for Immune TherapySemantic proximity Read ↗

Phenotype and function of MAIT cells in patients with alveolar echinococcosis.Semantic proximity Read ↗

[Changes of Phenotype and Phagocytosis of Peritoneal Macrophages in Mice Infected with the Larval-stage of Echinococcus granulosus].Semantic proximity Read ↗

Immunological mechanisms involved in macrophage activation and polarization in schistosomiasisSemantic proximity Read ↗

The macrophage polarization in Entamoeba histolytica infection modulation by the C fragment of the intermediate subunit of Gal/GalNAc-inhibitable lectinSemantic proximity Read ↗

High PD-1 and CTLA-4 expression correlates with host immune suppression in patients and a mouse model infected with Echinococcus multilocularisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.