Article
The Regulatory Roles of Toll-Like Receptor 4 in Secretions of Type 1/Type 2 Relative Cytokines by Splenocytes and Dendritic Cells Exposed to Clonorchis sinensis Excretory/Secretory Products.
Inflammation - 1 Feb 2018
Hua Hui, Du Ying, Ma Rui, Zhang Bei-Bei, Yu Qian, Li Bo, Xu Jiang-Tao, Li Xiang-Yang, Tang Ren-Xian, Yan Chao, Zheng Kui-Yang
Abstract excerpt
The roles of TLR4 in mediation of innate immune response and in regulation of adaptive immune responses triggered by Clonorchis sinensis remain unknown. In the present study, splenocytes derived from C3H/HeN (TLR4 wild ) and C3H/Hej mice (TLR4 mut ) that were infected with 45 metacercariae of C. sinensis were harvested, then stimulated by C. sinensis excretory/secretory products (ESP) or medium (control) for...
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