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Article

A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources

10 Aug 2015

Abstract excerpt

INTRODUCTION: Patients with systemic lupus erythematosus (SLE) have a decreased ability to clear cell remnants and multiple deficiencies in the ability to degrade cellular chromatin have been linked to the disease. Since the discovery of neutrophil extracellular traps (NETs), a renewed interest has been sparked in this field of research with multiple studies reporting a decreased ability of patients with SLE to...

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Share to Blood disorders and treatments
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PMID: 26268365
DOI: 10.1186/s13075-015-0726-y

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