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Article

An Emerging Role for Anti-DNA Antibodies in Systemic Lupus Erythematosus

19 Nov 2023

Abstract excerpt

Anti-DNA antibodies are hallmark autoantibodies produced in systemic lupus erythematosus (SLE), but their pathogenetic role is not fully understood. Accumulating evidence suggests that some anti-DNA antibodies enter different types of live cells and affect the pathophysiology of SLE by stimulating or impairing these cells. Circulating neutrophils in SLE are activated by a type I interferon or other stimuli and...

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PMID: 38003689
DOI: 10.3390/ijms242216499

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