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Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA

2022-09-02

Abstract excerpt

<h4>Background</h4> Because circulating DNA (cirDNA) are mainly detected as mononucleosome-associated circulating DNA (mono-N cirDNA) in blood apoptosis has until now been considered as the main source of cirDNA. The mechanism of cirDNA release into the circulation, however, is still not fully understood. This work addresses that knowledge gap, working from the postulate that neutrophil extracellular traps (NET)...

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Literature Corpus work
81867f60-9fbb-5ed4-8c87-d50f79ecd9ab
DOI
10.1101/2022.09.01.506266
Open publication

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Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNADOI 10.1101/2022.09.01.506266
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