Article
Circulating microparticles in systemic Lupus Erythematosus.
Danish medical journal - 1 Nov 2012
Nielsen Christoffer Tandrup
Abstract excerpt
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease presenting with a wide array of clinical manifestations and an elusive pathogenesis. A characteristic feature in SLE is the occurrence of autoantibodies against chromatin, double-stranded DNA, and RNA-binding ribonucleoproteins. Observations of defective clearance of dying cells in SLE combined with the generation and exposure of nuclear...
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