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Article

Identification of a new amino acid mutation in the HN protein of NDV involved in pathogenicity.

Veterinary research - 20 Dec 2021

Chen Xi, Jia Yanqing, Wei Ning, Ye Chao, Hao Huafang, Xiao Sa, Wang Xinglong, Liu Haijin, Yang Zengqi

Abstract excerpt

The fusion (F) and haemagglutinin-neuraminidase (HN) proteins of Newcastle disease virus (NDV) are viral entry proteins and are recognized as the major virulence determinants. Previously, a lentogenic NDV virus (CE16) was derived from a mesogenic strain (CI10) through sequential passages in chick embryos. Whole-genome sequence analysis revealed that the two homologous strains shared the same F protein but...

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Identifiers

PMID: 34930432
DOI: 10.1186/s13567-021-01019-4
PMCID: PMC8686287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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