Article
PGWD: Integrating Personal Genome for Warfarin Dosing.
Interdisciplinary sciences, computational life sciences - 1 Mar 2016
Pan Yidan, Cheng Ronghai, Li Zhoufang, Zhao Yujun, He Jiankui
Abstract excerpt
Warfarin is a drug normally used in the prevention of thrombosis and the formation of blood clots. The dosage of warfarin is strongly affected by genetic variants of CYP2C9 and VKORC1 genes. Current technologies for detecting the variants of these genes are mainly based on real-time PCR. In recent years, due to the rapidly dropping cost of whole genome sequencing and genotyping, more and more people get their...
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