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Article

Structure-expression relationships of the 15-kDa selenoprotein gene. Possible role of the protein in cancer etiology.

The Journal of biological chemistry - 10 Nov 2000

Kumaraswamy E, Malykh A, Korotkov K V, Kozyavkin S, Hu Y, Kwon S Y, Moustafa M E, Carlson B A, Berry M J, Lee B J, Hatfield D L, Diamond A M, Gladyshev V N

Abstract excerpt

Selenium has been implicated in cancer prevention, but the mechanism and possible involvement of selenoproteins in this process are not understood. To elucidate whether the 15-kDa selenoprotein may play a role in cancer etiology, the complete sequence of the human 15-kDa protein gene was determined, and various characteristics associated with expression of the protein were examined in normal and malignant cells...

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PMID: 10945981
DOI: 10.1074/jbc.M004014200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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