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Article

A Functional Variant of the miR-15 Family Is Associated with a Decreased Risk of Esophageal Squamous Cell Carcinoma.

DNA and cell biology - 1 Sept 2020

Shao Yi, Guo Xudong, Zhao Lei, Shen Yi, Niu Chen, Wei Wenqiang, Liu Fen

Abstract excerpt

MicroRNAs (miRNAs)-related single-nucleotide polymorphisms (SNPs) have been shown to be implicated in the susceptibility to different types of cancer, including esophageal squamous cell carcinoma (ESCC). Identification of miRNA-related SNPs may provide candidate biomarkers for early diagnosis of ESCC. We performed a genome-wide microarray assay to identify differentially expressed miRNAs, which indicated that the...

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PMID: 32635759
DOI: 10.1089/dna.2020.5606

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