Article
Association between CTLA-4 gene polymorphism and ankylosing spondylitis: a case-control study.
International journal of clinical and experimental pathology - 1 Jan 2015
Wang Nai-Guo, Wang Da-Chuan, Tan Bing-Yi, Wang Feng, Yuan Ze-Nong
Abstract excerpt
AIMS: The aim of our study was to evaluate the association between CTLA-4 polymorphisms (+49A/G, -318C/T and CT60A/G) and ankylosing spondylitis (AS) susceptibility. METHODS: A total of 120 AS cases and healthy controls, matched on the age and gender, were enrolled in the study. Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP) were used to determine the gentypes of +49A/G, -318C/T...
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