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Article

The associations between PD-1, CTLA-4 gene polymorphisms and susceptibility to ankylosing spondylitis: a meta-analysis and systemic review.

Rheumatology international - 1 Jan 2016

Chen Si, Li Yuan, Deng Chuiwen, Li Jing, Wen Xiaoting, Wu Ziyan, Hu Chaojun, Zhang Shulan, Li Ping, Zhang Xuan, Zhang Fengchun, Li Yongzhe

Abstract excerpt

Previous surveys had evaluated the effects of the PD-1, CTLA-4 gene polymorphisms on susceptibility to ankylosing spondylitis (AS), but the results remained controversial. To briefly examine these consequences, a comprehensive meta-analysis was conducted to estimate the relationships between PD-1 rs11568821, rs2227982, rs2227981, CTLA-4 +49 A/G and -318 C/T polymorphisms and AS risk. The available articles dated...

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Share to Alleles
Share to CTLA-4 Antigen
Share to Genetic Predisposition to Disease
Share to Genotype
Share to Polymorphism, Single Nucleotide
Share to Programmed Cell Death 1 Receptor
Share to Spondylitis, Ankylosing

Source

Identifiers

PMID: 26232179
DOI: 10.1007/s00296-015-3327-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The associations between PD-1, CTLA-4 gene polymorphisms and susceptibility to ankylosing spondylitis: a meta-analysis and systemic review.PMID 26232179Read ↗

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