Article
Polymorphisms of cytotoxic T lymphocyte-associated antigen-4 and cytokine genes in Taiwanese patients with ankylosing spondylitis.
Tissue antigens - 1 Feb 2010
Lee W-Y, Chang Y-H, Lo M-K, Chang C-P, Yang S-C, Yang T-P, Ho K-T, Juan C-W, Shiau M-Y
Abstract excerpt
Cytokines, costimulatory and counter-regulatory molecules play important roles in the regulation of inflammatory response, and are good candidates involved in the development of ankylosing spondylitis (AS). This study investigated the genotypic distribution of proinflammatory cytokines and T-cell negative regulator cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) in healthy subjects and AS patients. Genomic...
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