Article
Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE).
American journal of hematology - 1 Nov 2015
Folsom Aaron R, Tang Weihong, Roetker Nicholas S, Heckbert Susan R, Cushman Mary, Pankow James S
Abstract excerpt
Elevated plasma concentrations of coagulation factor XI may increase risk of venous thromboembolism (VTE), but prospective data are limited. We studied prospectively the associations of plasma factor XI and a key F11 genetic variant with incident VTE in whites and African-Americans. We measured factor XI in 16,299 participants, initially free of VTE, in two prospective population cohorts. We also measured the F11...
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