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Article

Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Nov 2015

Lahoti Tejas S, Boyer Jacob A, Kusnadi Ann, Muku Gulsum E, Murray Iain A, Perdew Gary H

Abstract excerpt

The Ah receptor (AHR) is directly involved in the regulation of both innate and adaptive immunity. However, these activities are poorly understood at the level of gene regulation. The chemokine (c-c motif) ligand 20 (CCL20) plays a nonredundant role in the chemoattraction of C-C motif receptor 6 expressing cells (eg, T cells and others). A survey of promoter regions of chemokine genes revealed that there are...

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Source

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Identifiers

PMID: 26259605
DOI: 10.1093/toxsci/kfv178
PMCID: PMC4731409

Genes

AHR
ARNT
CCL20
HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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