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Article

Role of the xenobiotic receptor in inflammatory bowel disease.

Inflammatory bowel diseases - 1 May 2011

Arsenescu Razvan, Arsenescu Violeta, Zhong Jian, Nasser Munira, Melinte Razvan, Dingle R W Cameron, Swanson Hollie, de Villiers Willem J

Abstract excerpt

BACKGROUND: Gene-environment interplay modulates inflammatory bowel diseases (IBD). Dioxin-like compounds can activate the aryl hydrocarbon receptor (AhR) and alter macrophage function as well as T-cell polarization. We hypothesized that attenuation of the AhR signaling pathway will ameliorate colitis in a murine model of IBD. METHODS: Dextran sulfate sodium (DSS) colitis was induced in C57BL/6 AhR null mice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20878756
DOI: 10.1002/ibd.21463
PMCID: PMC3013235

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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