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Article

Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases.

International journal of molecular sciences - 28 Dec 2021

Cannon Alkeiver S, Nagarkatti Prakash S, Nagarkatti Mitzi

Abstract excerpt

For decades, activation of Aryl Hydrocarbon Receptor (AhR) was excluded from consideration as a therapeutic approach due to the potential toxic effects of AhR ligands and the induction of the cytochrome P450 enzyme, Cyp1a1, following AhR activation. However, it is now understood that AhR activation not only serves as an environmental sensor that regulates the effects of environmental toxins, but also as a key...

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Identifiers

PMID: 35008717
DOI: 10.3390/ijms23010288
PMCID: PMC8745713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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