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Article

The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value.

Pharmacology & therapeutics - 1 May 2018

Roman Ángel C, Carvajal-Gonzalez José M, Merino Jaime M, Mulero-Navarro Sonia, Fernández-Salguero Pedro M

Abstract excerpt

The aryl hydrocarbon receptor (AhR) is well-known for its major contributions to the cellular responses against environmental toxins and carcinogens. Notably, AhR has also emerged as a key transcription factor controlling many physiological processes including cell proliferation and apoptosis, differentiation, adhesion and migration, pluripotency and stemness. These novel functions have broadened our...

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PMID: 29258844
DOI: 10.1016/j.pharmthera.2017.12.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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