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Article

Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-κB.

The Journal of biological chemistry - 17 Jan 2014

Vogel Christoph F A, Khan Elaine M, Leung Patrick S C, Gershwin M Eric, Chang W L William, Wu Dalei, Haarmann-Stemmann Thomas, Hoffmann Alexander, Denison Michael S

Abstract excerpt

The aryl hydrocarbon receptor (AhR) is involved in the regulation of immune responses, T-cell differentiation, and immunity. Here, we show that inflammatory stimuli such as LPS induce the expression of AhR in human dendritic cells (DC) associated with an AhR-dependent increase of CYP1A1 (cytochrome P4501A1). In vivo data confirmed the elevated expression of AhR by LPS and the LPS-enhanced...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24302727
DOI: 10.1074/jbc.M113.505578
PMCID: PMC3894361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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