Article
Succinate Dehydrogenase (SDH)-Deficient Pancreatic Neuroendocrine Tumor Expands the SDH-Related Tumor Spectrum.
The Journal of clinical endocrinology and metabolism - 1 Oct 2015
Niemeijer Nicolasine D, Papathomas Thomas G, Korpershoek Esther, de Krijger Ronald R, Oudijk Lindsey, Morreau Hans, Bayley Jean-Pierre, Hes Frederik J, Jansen Jeroen C, Dinjens Winand N M, Corssmit Eleonora P M
Abstract excerpt
CONTEXT: Mutations in genes encoding the subunits of succinate dehydrogenase (SDH) can lead to pheochromocytoma/paraganglioma formation. However, SDH mutations have also been linked to nonparaganglionic tumors. OBJECTIVE: The objective was to investigate which nonparaganglionic tumors belong to the SDH-associated tumor spectrum. DESIGN: This was a retrospective cohort study. SETTING: The setting was a tertiary...
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