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Article

Functional relevance for associations between osteoporosis and genetic variants.

PloS one - 1 Jan 2017

Liu Kun, Tan Li-Jun, Wang Peng, Chen Xiang-Ding, Zhu Li-Hua, Zeng Qin, Hu Yuan, Deng Hong-Wen

Abstract excerpt

Osteoporosis is characterized by increased bone loss and deterioration of bone microarchitecture, which will lead to reduced bone strength and increased risk of fragility fractures. Previous studies have identified many genetic loci associated with osteoporosis, but functional mechanisms underlying the associations have rarely been explored. In order to explore the potential molecular functional mechanisms...

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Topics

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Share to Osteoporosis
Share to Bone Density
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Profiling

Share to LRP5 gene

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 28369098
DOI: 10.1371/journal.pone.0174808
PMCID: PMC5378394

Genes

RPL31
LRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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