Article
An integrative study ascertained SOD2 as a susceptibility gene for osteoporosis in Chinese.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2011
Deng Fei-Yan, Lei Shu-Feng, Chen Xiang-Ding, Tan Li-Jun, Zhu Xue-Zhen, Deng Hong-Wen
Abstract excerpt
Osteoporosis is characterized by low BMD and has strong genetic determination. However, specific genetic variants influencing BMD and contributing to the pathogenesis of osteoporosis are largely uncharacterized. Current genetic studies in bone, which are aimed at identification of osteoporosis risk genes, are focused mostly on DNA, RNA, or the protein level individually, lacking integrative evidence from the...
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