Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic spectra of biliary tract cancer.

Nature genetics - 1 Sept 2015

Nakamura Hiromi, Arai Yasuhito, Totoki Yasushi, Shirota Tomoki, Elzawahry Asmaa, Kato Mamoru, Hama Natsuko, Hosoda Fumie, Urushidate Tomoko, Ohashi Shoko, Hiraoka Nobuyoshi, Ojima Hidenori, Shimada Kazuaki, Okusaka Takuji, Kosuge Tomoo, Miyagawa Shinichi, Shibata Tatsuhiro

Abstract excerpt

The incidence of biliary tract cancer (BTC), including intrahepatic (ICC) and extrahepatic (ECC) cholangiocarcinoma and gallbladder cancer, has increased globally; however, no effective targeted molecular therapies have been approved at the present time. Here we molecularly characterized 260 BTCs and uncovered spectra of genomic alterations that included new potential therapeutic targets. Gradient spectra of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biliary Tract Neoplasms
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Oncogene Proteins, Fusion

Share to Point Mutation

Share to Proto-Oncogene Proteins c-ets

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to Receptor, Fibroblast Growth Factor, Type 2

Source

Identifiers

PMID: 26258846
DOI: 10.1038/ng.3375

Genes

BTC
ELF3
FGFR2
PRKACA
PRKACB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic spectra of biliary tract cancer.PMID 26258846Read ↗

Clinical, Genomic, and Transcriptomic Data Profiling of Biliary Tract Cancer Reveals Subtype-Specific Immune SignaturesSemantic proximity Read ↗

Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targetsSemantic proximity Read ↗

Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer.Semantic proximity Read ↗

Actionable genomic landscape of biliary tract cancer in the Indian population.Semantic proximity Read ↗

Molecular genomic landscapes of hepatobiliary cancer.Semantic proximity Read ↗

Global patterns of mutational profiles in biliary tract cancer.Semantic proximity Read ↗

Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancerSemantic proximity Read ↗

Translating cancer genomics for precision oncology in biliary tract cancers.Semantic proximity Read ↗

Comparative analysis of genomic profiles and clinical outcomes in cholangiocarcinoma and gallbladder cancer.Semantic proximity Read ↗

Mutational spectrum and precision oncology for biliary tract carcinoma.Semantic proximity Read ↗

Genomics driven precision oncology in advanced biliary tract cancer improves survival.Semantic proximity Read ↗

The potential role of comprehensive genomic profiling to guide targeted therapy for patients with biliary cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.