Article
Mutational spectrum and precision oncology for biliary tract carcinoma.
Theranostics - 1 Jan 2021
Lin Jianzhen, Cao Yinghao, Yang Xu, Li Guangyu, Shi Yang, Wang Dongxu, Long Junyu, Song Yang, Mao Jinzhu, Xie Fucun, Bai Yi, Zhang Lei, Yang Xiaobo, Wan Xueshuai, Wang Anqiang, Guan Mei, Zhao Lin, Hu Ke, Pan Jie, Huo Li, Lu Xin, Mao Yilei, Sang Xinting, Zhang Henghui, Wang Kai, Wang Xiaoyue, Zhao Haitao
Abstract excerpt
Background: The genomic spectrum of biliary tract carcinoma (BTC) has been characterized and is associated with distinct anatomic and etiologic subtypes, yet limited studies have linked genomic alterations with personalized therapies in BTC patients. Methods: This study analyzed 803 patients with BTC:164 with gallbladder cancer, 475 with intrahepatic cholangiocarcinoma (ICC) and 164 with extrahepatic...
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