Article
Translating cancer genomics for precision oncology in biliary tract cancers.
Discovery medicine - 1 Jan 2000
Haber Philipp K, Sia Daniela
Abstract excerpt
Biliary tract cancers (BTC), which include cholangiocarcinoma (both intra- and extrahepatic) and gallbladder, represent a heterogeneous group of malignancies with relatively low-incidence and poor prognosis. Therapeutic options for BTC patients at advanced stage are severely limited and palliative chemotherapy remains the maintreatment option. In the past decade, genome profiling via next-generation sequencing of...
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