Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomics driven precision oncology in advanced biliary tract cancer improves survival.

Neoplasia (New York, N.Y.) - 1 Aug 2023

Kumar-Sinha Chandan, Vats Pankaj, Tran Nguyen, Robinson Dan R, Gunchick Valerie, Wu Yi-Mi, Cao Xuhong, Ning Yu, Wang Rui, Rabban Erica, Bell Janice, Shankar Sunita, Mannan Rahul, Zhang Yuping, Zalupski Mark M, Chinnaiyan Arul M, Sahai Vaibhav

Abstract excerpt

BACKGROUND: Biliary tract cancers (BTCs) including intrahepatic, perihilar, and distal cholangiocarcinoma as well as gallbladder cancer, are rare but aggressive malignancies with few effective standard of care therapies. METHODS: We implemented integrative clinical sequencing of advanced BTC tumors from 124 consecutive patients who progressed on standard therapies (N=92 with MI-ONCOSEQ and N=32 with commercial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biliary Tract Neoplasms

Share to Cholangiocarcinoma and Gallbladder Cancer Studies

Share to Genomics

Share to Mutation

Share to Pancreatic and Hepatic Oncology Research

Share to Precision Medicine

Source

Open in PubMed Open full text

Identifiers

PMID: 37267699
DOI: 10.1016/j.neo.2023.100910
PMCID: PMC10245336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomics driven precision oncology in advanced biliary tract cancer improves survival.PMID 37267699Read ↗

Translating cancer genomics for precision oncology in biliary tract cancers.Semantic proximity Read ↗

Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer.Semantic proximity Read ↗

Real-world Analysis of Treatment Patterns, Clinical Outcomes, and Molecular Profiling in Advanced Biliary Tract Cancer.Semantic proximity Read ↗

Mutational spectrum and precision oncology for biliary tract carcinoma.Semantic proximity Read ↗

Effect of comprehensive cancer genomic profiling on therapeutic strategies and clinical outcomes in patients with advanced biliary tract cancer: A prospective multicenter studySemantic proximity Read ↗

Genomic spectra of biliary tract cancer.Semantic proximity Read ↗

Targeted Therapies in Advanced Biliary Tract Cancer: An Evolving ParadigmSemantic proximity Read ↗

Biliary cancer: Utility of next-generation sequencing for clinical management.Semantic proximity Read ↗

Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targetsSemantic proximity Read ↗

Comparative analysis of genomic profiles and clinical outcomes in cholangiocarcinoma and gallbladder cancer.Semantic proximity Read ↗

Targeted deep sequencing contributes to guiding personalized targeted therapy for advanced biliary tract cancer patients with non‑radical resection: A real‑world study.Semantic proximity Read ↗

Targeted Therapy Improves Real-World Survival in Patients with Molecularly Matched Advanced Biliary Tract CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.