Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bioinformatic processing to identify single nucleotide polymorphism that potentially affect Ape1 function.

Mutation research - 17 Jun 2011

Yu Eizadora T, Hadi Masood Z

Abstract excerpt

Inactivation of DNA damage response mechanisms is associated with several disease syndromes, including cancer, aging and neurodegeneration. A major corrective pathway for alkylation or oxidative DNA damage is base excision repair (BER). As part of an effort to identify variation in DNA repair gen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Computational Biology
Share to Databases, Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-(Apurinic or Apyrimidinic Site) Lyase

Share to DNA Repair

Share to Expressed Sequence Tags

Share to Polymorphism, Single Nucleotide

Share to Software

Source

Identifiers

PMID: 20633698
DOI: 10.1016/j.mrgentox.2010.06.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20633698-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bioinformatic processing to identify single nucleotide polymorphism that potentially affect Ape1 function.PMID 20633698Read ↗

Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes.Semantic proximity Read ↗

Functional characterization of Ape1 variants identified in the human population.Semantic proximity Read ↗

Molecular and structural characterization of disease-associated APE1 polymorphisms.Semantic proximity Read ↗

Identifying functional genetic variants in DNA repair pathway using protein conservation analysis.Semantic proximity Read ↗

In silico searching for disease-associated functional DNA variants.Semantic proximity Read ↗

Bioinformatic tools for identifying disease gene and SNP candidates.Semantic proximity Read ↗

Genetic variants of the DNA repair genes from Exome Aggregation Consortium (EXAC) database: significance in cancer.Semantic proximity Read ↗

Applications of computational algorithm tools to identify functional SNPs.Semantic proximity Read ↗

Association of DNA Repair Gene APE1 Asp148Glu Polymorphism with Breast Cancer Risk.Semantic proximity Read ↗

APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation.Semantic proximity Read ↗

Investigating the structural impacts of I64T and P311S mutations in APE1-DNA complex: a molecular dynamics approach.Semantic proximity Read ↗

Functional assessment of population and tumor-associated APE1 protein variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.