Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic deregulations in chordoma

10 Aug 2015

Abstract excerpt

Chordoma is a rare type of malignant bone tumour arising from remnant notochord and prognosis of patients with it remains poor as its molecular and genetic mechanisms are not well understood. Increasing evidence has demonstrated that epigenetic mechanisms (DNA methylation, histone modification and nucleosome remodelling), play a crucial role in the pathogenesis of many diseases. Aberrant epigenetic patterns are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Tumor Diagnosis and Treatments
Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26256106
DOI: 10.1111/cpr.12204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic deregulations in chordomaPMID 26256106Read ↗

Genome-wide DNA methylation profiling of recurrent and non-recurrent chordomasSemantic proximity Read ↗

Dysregulated Epigenetics of Chordoma: Prognostic Markers and Therapeutic TargetsSemantic proximity Read ↗

Chordoma: Genetics and Contemporary Management.Semantic proximity Read ↗

DNA methylation, combined with RNA sequencing, provide novel insight into molecular classification of chordomas and their microenvironmentSemantic proximity Read ↗

DNA methylation, combined with RNA sequencing, provide novel insight into molecular classification of chordomas and their microenvironmentSemantic proximity Read ↗

Chordoma Characterization of Significant Changes of the DNA Methylation PatternSemantic proximity Read ↗

Recent advances in understanding and managing chordomas: an updateSemantic proximity Read ↗

Gene Expression Profiling Identifies Two Chordoma Subtypes Associated with Distinct Molecular Mechanisms and Clinical OutcomesSemantic proximity Read ↗

Methylation-based reclassification and risk stratification of skull-base chordomasSemantic proximity Read ↗

The epigenomics of sarcoma.Semantic proximity Read ↗

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implicationsSemantic proximity Read ↗

From Histology to Multi-Omics: Review of Chordoma Classification and Its Clinical ImplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.