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Article

The epigenomics of sarcoma.

Nature reviews. Cancer - 1 Oct 2020

Nacev Benjamin A, Jones Kevin B, Intlekofer Andrew M, Yu Jamie S E, Allis C David, Tap William D, Ladanyi Marc, Nielsen Torsten O

Abstract excerpt

Epigenetic regulation is critical to physiological control of development, cell fate, cell proliferation, genomic integrity and, fundamentally, transcriptional regulation. This epigenetic control occurs at multiple levels including through DNA methylation, histone modification, nucleosome remodelling and modulation of the 3D chromatin structure. Alterations in genes that encode chromatin regulators are common...

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Share to Cell Transformation, Neoplastic
Share to Chromatin
Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Epigenomics

Share to Gene Expression Regulation, Neoplastic

Share to Sarcoma

Source

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Identifiers

PMID: 32782366
DOI: 10.1038/s41568-020-0288-4
PMCID: PMC8380451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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