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Article

A Validated Phenotyping Algorithm for Genetic Association Studies in Age-related Macular Degeneration.

Scientific reports - 10 Aug 2015

Simonett Joseph M, Sohrab Mahsa A, Pacheco Jennifer, Armstrong Loren L, Rzhetskaya Margarita, Smith Maureen, Geoffrey Hayes M, Fawzi Amani A

Abstract excerpt

Age-related macular degeneration (AMD), a multifactorial, neurodegenerative disease, is a leading cause of vision loss. With the rapid advancement of DNA sequencing technologies, many AMD-associated genetic polymorphisms have been identified. Currently, the most time consuming steps of these studies are patient recruitment and phenotyping. In this study, we describe the development of an automated algorithm to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26255974
DOI: 10.1038/srep12875
PMCID: PMC4530462

Genes

CFH
ARMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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