Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration.

Human genomics - 1 Jul 2011

Hageman Gregory S, Gehrs Karen, Lejnine Serguei, Bansal Aruna T, Deangelis Margaret M, Guymer Robyn H, Baird Paul N, Allikmets Rando, Deciu Cosmin, Oeth Paul, Perlee Lorah T

Abstract excerpt

Predictive tests for estimating the risk of developing late-stage neovascular age-related macular degeneration (AMD) are subject to unique challenges. AMD prevalence increases with age, clinical phenotypes are heterogeneous and control collections are prone to high false-negative rates, as many c...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Choroidal Neovascularization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement C2

Share to Complement C3

Share to Complement Factor B

Share to Complement Factor H

Share to Macular Degeneration

Share to Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 21807600
DOI: 10.1186/1479-7364-5-5-420
PMCID: PMC3525964

Genes

ARMS2
CFB
CFH
CFHR4
CFHR5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21807600-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration.PMID 21807600Read ↗

Inclusion of genotype with fundus phenotype improves accuracy of predicting choroidal neovascularization and geographic atrophy.Semantic proximity Read ↗

Genome-Wide Meta-analysis Identifies Risk Loci and Improves Disease Prediction of Age-Related Macular Degeneration.Semantic proximity Read ↗

Clinical applications of age-related macular degeneration genetics.Semantic proximity Read ↗

Nongenetic risk factors for neovascular age-related macular degeneration.Semantic proximity Read ↗

Predictive models of choroidal neovascularization and geographic atrophy incidence applied to clinical trial design.Semantic proximity Read ↗

Large-scale genetic analysis of age-related macular degeneration (AMD) drug targets highlights precision therapy opportunities for patients with high polygenic riskSemantic proximity Read ↗

A Validated Phenotyping Algorithm for Genetic Association Studies in Age-related Macular Degeneration.Semantic proximity Read ↗

Rare complement factor I variants associated with reduced macular thickness and age-related macular degeneration in the UK Biobank.Semantic proximity Read ↗

Genetic analysis of age-related macular degeneration highlights precision therapy opportunities for patients with high polygenic riskSemantic proximity Read ↗

Differences in the Genetic Susceptibility to Age-Related Macular Degeneration Clinical Subtypes.Semantic proximity Read ↗

GWAS-based Machine Learning for Prediction of Age-Related Macular Degeneration RiskSemantic proximity Read ↗

Risk assessment model for development of advanced age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.