Article
Genetic Risk Evaluation in Wet Age-Related Macular Degeneration Treatment Response.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde - 1 Jan 2016
Chaudhary Varun, Brent Michael, Lam Wai-Ching, Devenyi Robert, Teichman Joshua, Mak Michael, Barbosa Joshua, Kaur Harneel, Carter Ronald, Farrokhyar Forough
Abstract excerpt
OBJECTIVE: To evaluate the pharmacogenetic relationship between CFH haplotypes and single nucleotide polymorphisms (SNPs) with response to ranibizumab treatment for neovascular age-related macular degeneration (nAMD). PATIENTS AND METHODS: This was a prospective cohort study involving 70 treatment-naive nAMD patients. Patients were genotyped for CFH haplotypes and SNPs in the C3, ARMS2, and mtDNA genes. Visual...
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