Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inclusion of genotype with fundus phenotype improves accuracy of predicting choroidal neovascularization and geographic atrophy.

Ophthalmology - 1 Sept 2013

Perlee Lorah T, Bansal Aruna T, Gehrs Karen, Heier Jeffrey S, Csaky Karl, Allikmets Rando, Oeth Paul, Paladino Toni, Farkas Daniel H, Rawlings P Lyle, Hageman Gregory S

Abstract excerpt

PURPOSE: The accuracy of predicting conversion from early-stage age-related macular degeneration (AMD) to the advanced stages of choroidal neovascularization (CNV) or geographic atrophy (GA) was evaluated to determine whether inclusion of clinically relevant genetic markers improved accuracy beyond prediction using phenotypic risk factors alone. DESIGN: Cohort study. PARTICIPANTS: White, non-Hispanic subjects...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins
Share to Choroidal Neovascularization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement Factor H

Share to Complement System Proteins

Share to Eye Proteins

Share to Fundus Oculi

Share to Geographic Atrophy

Share to Macular Degeneration

Source

Open in PubMed Open full text

Identifiers

PMID: 23523162
DOI: 10.1016/j.ophtha.2013.02.007
PMCID: PMC3695024

Genes

ARMS2
CFH
CFHR4
CFHR5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inclusion of genotype with fundus phenotype improves accuracy of predicting choroidal neovascularization and geographic atrophy.PMID 23523162Read ↗

Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration.Semantic proximity Read ↗

Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.Semantic proximity Read ↗

Rare and Common Genetic Variants, Smoking and Higher Body Mass Index Are Associated with Earlier Age of Progression to Geographic Atrophy and Neovascular Advanced Stages of Macular Degeneration in a Prospective AnalysisSemantic proximity Read ↗

Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors.Semantic proximity Read ↗

The contribution of genetic factors to phenotype and progression of drusen in early age-related macular degeneration.Semantic proximity Read ↗

Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors.Semantic proximity Read ↗

Association between Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular DegenerationSemantic proximity Read ↗

Correlation of Color Fundus Photograph Grading with Risks of Early Age-related Macular Degeneration by using Automated OCT-derived Drusen Measurements.Semantic proximity Read ↗

Development of a Genotype Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium.Semantic proximity Read ↗

Risk assessment model for development of advanced age-related macular degeneration.Semantic proximity Read ↗

Clinical applications of age-related macular degeneration genetics.Semantic proximity Read ↗

Predictive models of choroidal neovascularization and geographic atrophy incidence applied to clinical trial design.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.