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Article

Linkage of catalysis and 5' end recognition in ribonuclease RNase J.

Nucleic acids research - 18 Sept 2015

Pei Xue-Yuan, Bralley Patricia, Jones George H, Luisi Ben F

Abstract excerpt

In diverse bacterial species, the turnover and processing of many RNAs is mediated by the ribonuclease RNase J, a member of the widely occurring metallo-β-lactamase enzyme family. We present crystal structures of Streptomyces coelicolor RNase J with bound RNA in pre- and post-cleavage states, at 2.27 Å and 2.80 Å resolution, respectively. These structures reveal snapshots of the enzyme cleaving substrate...

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Identifiers

PMID: 26253740
DOI: 10.1093/nar/gkv732
PMCID: PMC4652760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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