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Article

A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility.

Oncology reports - 1 Oct 2015

Yan Shi, Yuan Cunzhong, Yang Qifeng, Li Xiaoyan, Yang Ning, Liu Xiaoyan, Dong Ruihua, Zhang Xi, Yuan Zeng, Zhang Ning, Kong Beihua

Abstract excerpt

Calcium-sensing receptor (CaSR) is a G-protein‑ coupled receptor that senses blood calcium. In vivo, CaSR is required for normal epidermal differentiation by mediating calcium signaling. CaSR was confirmed to be a tumor suppressor in colon and breast cancer. The single-nucleotide polymorphism (SNP) rs17251221, located on the intron, is a genetic variation of the CaSR gene. We analyzed rs17251221 in ovarian cancer...

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Identifiers

PMID: 26252839
DOI: 10.3892/or.2015.4179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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