Genetic polymorphism of calcium-sensing receptor in women with breast cancer.

doi:10.1007/s12032-018-1089-4

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Genetic polymorphism of calcium-sensing receptor in women with breast cancer.

Medical oncology (Northwood, London, England) - 31 Jan 2018

Campos-Verdes Larysse Maira, da Silva-Sampaio João Paulo, Costa-Silva Danylo Rafhael, de Oliveira Victor Alves, Junior Airton Mendes Conde, Silva Vladimir Costa, Alencar Airlane Pereira, Campelo Viriato, Lopes-Costa Pedro Vitor, Gebrim Luiz Henrique, da Silva Benedito Borges

Abstract excerpt

Breast cancer is a disease of unknown etiology, whose major risk factors are genetic alterations. Polymorphism of the calcium-sensing receptor (CaSR) has been a focus of some recent studies, due to a probable association with breast cancer risk and tumor aggressiveness. A relationship between polymorphic rs17251221 variant of the CaSR gene, and allele G (considered a gain-of-function mutation) and breast cancer...

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PMID: 29387985
DOI: 10.1007/s12032-018-1089-4

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