Association of calcium sensing receptor polymorphisms at rs1801725 with circulating calcium in breast cancer patients.

doi:10.1186/s12885-017-3502-3

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Article

Association of calcium sensing receptor polymorphisms at rs1801725 with circulating calcium in breast cancer patients.

BMC cancer - 2 Aug 2017

Wang Li, Widatalla Sarrah E, Whalen Diva S, Ochieng Josiah, Sakwe Amos M

Abstract excerpt

BACKGROUND: Breast cancer (BC) patients with late-stage and/or rapidly growing tumors are prone to develop high serum calcium levels which have been shown to be associated with larger and aggressive breast tumors in post and premenopausal women respectively. Given the pivotal role of the calcium sensing receptor (CaSR) in calcium homeostasis, we evaluated whether polymorphisms of the CASR gene at rs1801725 and...

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PMID: 28764683
DOI: 10.1186/s12885-017-3502-3
PMCID: PMC5540567

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