Article
Neonatal Respiratory Failure with Retarded Perinatal Lung Maturation in Mice Caused by Reticulocalbin 3 Disruption.
American journal of respiratory cell and molecular biology - 1 Mar 2016
Jin Jiawei, Li Yongchao, Ren Jiangong, Man Lam Sin, Zhang Yidi, Hou Yu, Zhang Xiaojuan, Xu Rener, Shui Guanghou, Ma Runlin Z
Abstract excerpt
Reticulocalbin 3 (Rcn3) is an endoplasmic reticulum lumen protein localized to the secretory pathway. As a Ca2t-binding protein of 45 kDa (Cab45)/Rcn/ER Ca2t-binding protein of 55 kDa (ERC45)/calumenin (CREC) family member, Rcn3 is reported to function as a chaperone protein involved in protein synthesis and secretion; however, the biological role of Rcn3 is largely unknown. The results presented here, for the...
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