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Article

Genetic and non-genetic determinants of thymic epithelial cell number and function.

Scientific reports - 4 Sept 2017

Nagakubo Daisuke, Krauth Brigitte, Boehm Thomas

Abstract excerpt

The thymus is the site of T cell development in vertebrates. In general, the output of T cells is determined by the number of thymic epithelial cells (TECs) and their relative thymopoietic activity. Here, we show that the thymopoietic activity of TECs differs dramatically between individual mouse strains. Moreover, in males of some strains, TECs perform better on a per cell basis than their counterparts in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28871142
DOI: 10.1038/s41598-017-10746-8
PMCID: PMC5583284

Genes

TEC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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