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Article

Treatment failure with DAA therapy: Importance of resistance.

Journal of hepatology - 1 Jun 2021

Sarrazin Christoph

Abstract excerpt

Viral resistance is a major reason for virological failure in patients being treated with direct-acting antivirals (DAAs) for chronic HCV infection. However, the importance of viral resistance mainly depends on the DAA regimen and HCV genotype. For first-line therapy with glecaprevir/pibrentasvir (G/P) or velpatasvir/sofosbuvir (VEL/SOF) no general baseline resistance analysis is required because of the high...

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Identifiers

PMID: 33716089
DOI: 10.1016/j.jhep.2021.03.004

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