Article
Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
Inflammatory bowel diseases - 1 Nov 2015
Ananthakrishnan Ashwin N, Cagan Andrew, Cai Tianxi, Gainer Vivian S, Shaw Stanley Y, Churchill Susanne, Karlson Elizabeth W, Murphy Shawn N, Kohane Isaac, Liao Katherine P, Xavier Ramnik J
Abstract excerpt
BACKGROUND: The accuracy and utility of electronic health record (EHR)-derived phenotypes in replicating genotype-phenotype relationships have been infrequently examined. Low circulating vitamin D levels are associated with severe outcomes in inflammatory bowel disease (IBD); however, the genetic basis for vitamin D insufficiency in this population has not been examined previously. METHODS: We compared the...
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